Dr. Sharad Wakode profile photo

Dr. Sharad Wakode

Professor

DIPSAR

Google Scholar

Educational Qualifications

M.Pharm, PhD.

Area of Specialization / Research

Synthesis and development of new medicinal heterocyclic scaffold and investigation of their biological activities such as anti-inflammatory, anti-diabetic, anti-Alzheimer. Analytical method development, stability studies and validation of newer finished products and formulations. Phytochemical investigations i.e. isolation, purification and characterization of its chemical constituents from selected Medicinal plants and screening them Biological activity.

Notable Publications

  1. 1.

    Solid Lipid Nanoparticles: Synthesis, Microstructural Elucidations and Future Prospects, SB Kumbhar, VR Shinde, RG Jadhao, PP Warade, PR Patil, S Wakode , …Systematic Reviews in Pharmacy, 2021,13 (4) 417-429.

    2021
  2. 2.

    GC/MS analysis of Adhatoda vasica leaf and flower, S Agnihotri, S Wakode , M Ali, Indian Drugs, 2022, 59,3,67-68.

    2022
  3. 3.

    Role of Gut Microbiota and Probiotic in Chronic Fatigue Syndrome,

  4. 4.

    A Sharma, S Wakode , S Sharma, F Fayaz, Probiotic Research in Therapeutics, 2022, 211-236.

    2022
  5. 5.

    Structure-based pharmacophore mapping and virtual screening of natural products to identify polypharmacological inhibitor against c-MET/EGFR/VEGFR-2, DA Varma, M Singh, S Wakode , NE Dinesh, S Vinaik, S Asthana, M Tiwari, Journal of Biomolecular Structure and Dynamics, 2022,1-15.

    2022
  6. 6.

    Design and synthesis of amino acid derivatives of substituted benzimidazoles and pyrazoles as Sirt1 inhibitors, N Purushotham, M Singh, B Paramesha, V Kumar, S Wakode , …RSC advances, 2022,12 (7), 3809-3827.

    2022
  7. 7.

    Logical synthetic strategies and structure-activity relationship of indolin-2-one hybrids as small molecule anticancer agents: An overview, P Chaudhari, S Bari, S Surana, A Shirkhedkar, S Wakode , et al. Journal of Molecular Structure, 2022, 20241247, 131280.

    2022
  8. 8.

    Chemical Characterization and Anti-Inflammatory Activity of Phytoconstituents from Swertia alata, S Bajaj, S Wakode et al., Plants, 2021, 10, 1109.

    2021
  9. 9.

    Contemporary advances of cyclic molecules proposed for inflammation, K Neha, S Wakode , European Journal of Medicinal Chemistry, 2021, 113493.

    2021
  10. 10.

    A Review: Synthesis and Pharmacological Profile of [1, 5]-Benzothiazepine, S Khasimbi, F Ali, K Neha, Sharad Wakode , G Chauhan, Letters in Organic Chemistry, 2021.

    2021
  11. 11.

    Molecular Dynamics Simulation Reveals New Pocket for the Design of Novel Amino Acid Coupled Sirt1 Selective Inhibitor, M Singh, M Srivastava, N Purushotham, B Paramesha, SR Wakode, B Poojary, Banerjee, SK Asthana, Biophysical Journal, 2020, 118(3), 207a.

    2020
  12. 12.

    Effect of environmental toxicants on neuronal functions, S Sharma, S Wakode, A Sharma et al., Environmental Science and Pollution Research, 2020, 27(36) .

    2020
  13. 13.

    Celiac disease and its clinical manifestations, P Sharma, S Khasimbi, S Wakode , International Journal of Celiac Disease , 2020, 8(1), 22-27.

    2020
  14. 14.

    An Overview of Piperazine Scaffold as Promising Nucleus for Different Therapeutic Targets, A Sharma, S Wakode, F Fayaz, S Khasimbi, FH Pottoo, A Kaur, Current Pharmaceutical Design, 2020, 35, 4373-4385.

    2020
  15. 15.

    Investigating the Role of N-Terminal Domain in Phosphodiesterase 4B-Inhibition by Molecular Dynamics Simulation, V Sharma, S Wakode, Journal of Biomolecular Structure and Dynamics, 2020, 39 (12), 4270-4278.

    2020
  16. 16.

    Denouement of Chemicals on Amyotrophic Lateral Sclerosis: Is Green Chemistry the Answer, A Sharma, S Wakode et al ., Medicinal Chemistry, 2020, 16 (8), 1058-1068.

    2020
  17. 17.

    Biological signatures of Alzheimer’s Disease, P Sharma, A Sharma, F Fayaz, S Wakode , FH Pottoo, Current Topics In Medicinal Chemistry , 2020, 20,770-781.

    2020
  18. 18.

    HPLC method development and validation: simultaneous determination of Flibanserin and Caffein , P Sharma, M Dahiya, S Wakode , R Rani, Journal of Pharmaceutical Research, 2020, 4(3), 000213.

    2020
  19. 19.

    Valuable Insight into Recent Biological Activities of Different Benzimidazoles, D Insa, S Wakode, A Sharma, Scholars Academic Journal of Pharmacy, 2019, 1(3), 1-22.

    2019
  20. 20.

    Canagliflozin : A Review with Emphasis on Pharmacological Effects, R Kumar, S Wakode, Scholars Academic Journal of Pharmacy, 2019, 257-262

    2019
  21. 21.

    Ultrasound- Assisted Facile Synthesis of Nanostructured Hybrid Vesicle for the Nasal Delivery of Indomethacin: Response Surface Optimisation, Microstructure, and Stability, SS Patil , DD Kumbhar , JV Manwar , RG Jadhao , RL Bakal , S Wakode , AAPS PharmSciTech, 2019, 29,97.

    2019
  22. 22.

    Benzoxazole: A mini review, A Pasricha, S Wakode , F Fayaz, C Chhabra, World Journal of Pharmaceutical Sciences, 2018, 6(8)

    2018
  23. 23.

    Step-up in liquid chromatography from HPLC to UPLC: A comparative and comprehensive review, K Sahani, S Wakode , The Pharma Innovation Journal, 2018,7(8), 342-347.

    2018
  24. 24.

    Synthesis, biological evaluation and docking study of N-(2-(3,4,5- trimethoxybenzyl)benzoxazole-5-yl) benzamide derivatives as selective COX-2 inhibitor and anti-inflammatory agents, A Kaur, DP Pathak, V Sharma, B Narasimhan, P Sharma, R Mathur, S Wakode , Biorganic Chemisrty, 2018, 81, 191-202.

    2018
  25. 25.

    Synthesis, Cyclooxygenase-2 Inhibition, Anti-inflammatory Evaluation and Docking Study of Substituted-N-(3,4,5-trimethoxyphenyl)-benzo[d] oxazole derivatives, A Kaur, S Wakode , DP Pathak, V Sharma, , AK Shakya, Medicinal Chemistry, 2018, 14, 660-673.

    2018
  26. 26.

    Synthesis, molecular docking, and pharmacological evaluation of N-(2-(3,5-dimethoxyphenyl)benzoxazole-5-yl)benzamide derivatives as selective COX-2 inhibitors and anti-inflammatory agents, A Kaur, DP Pathak, V Sharma, S Wakode, Archiv der Pharmazie, 2018, 351.6, 1800008

    2018
  27. 27.

    Synthesis, biological evaluation and docking study of a new series of di-substituted benzoxazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents, A Kaur, S Wakode , DP Pathak, V Sharma, Bioorganic and medicinal chemistry, 2018, 26, 891-901

    2018
  28. 28.

    5, 6-Dihydropyrimidine-1 (2H)-carbothioamides: synthesis, in vitro GABA-AT screening, anticonvulsant activity and molecular modelling study, M Sahu, N Siddiqui, V Sharma, S Wakode , Bioorganic chemistry, 2018, 77, 56-67.

    2018
  29. 29.

    Synthesis, biological evaluation and docking study of a new series of di-substituted benzoxazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents, A Kaur, DP Pathak, V Sharma, S Wakode , Bioorganic & Medicinal Chemistry, 2018, 26(4), 891-902.

    2018
  30. 30.

    Simultaneous HPTLC analysis and In-vitro antileishmanic activity of various secondary metabolites present in extract of the traditional medicinal herb Artabortrys hexapetalus , S Bajaj, S Wakode , Washim Khan, S Kumar, S Manchanda, Ayu, 2018, 39(2):92.

    2018
  31. 31.

    Comparative in-vitro antioxidant, anti-inflammatory and antidiabetic activity of standardized polar extracts of S alata , S Bajaj , S Wakode, MOJ drug design development and therapy, 2018, 2(3), 151-155.

    2018
  32. 32.

    Synthesis, Characterisation and Antimicrobial Activity of Morpholine mannich base derivatives, H Amin , S Wakode , RK Tonk, International Journal Of Pharmaceutical Sciences And Research, 2018, 9(7), 2760-2766

    2018
  33. 33.

    Synthesis and Biological Evaluation of Some New 5-Acylamino-2-(3,4,5- Trimethoxyphenyl)Benzoxazoles as Potential Antibacterial and Anti-inflammatory Agents, A Kaur, S Wakode , DP Pathak, P Sharma, Indian Journal of Heterocyclic Chemistry, 2017, 27, 347-354.

    2017
  34. 34.

    Structural insight into selective phosphodiesterase 4B inhibitors: pharmacophore-based virtual screening, docking, and molecular dynamics simulations, V Sharma, S Wakode , Journal of Biomolecular Structure and Dynamics, 2017, 35 (6), 1339-1349.

    2017
  35. 35.

    Design, synthesis and evaluation of newer 5,6-dihydropyrimidine-2(1H)-thiones as GABA-AT inhibitors for anticonvulsant potential, M Sahu, N Siddiqui, R Iqbal, V Sharma, S Wakode , Bioorganic Chemistry, 2017, 74, 166-178.

    2017
  36. 36.

    Design, synthesis and docking study of Pyrimidine-Triazine hybrids for GABA estimation in animal epilepsy models, M Sahu, N Siddiqui, MJ Naim, O Alam, MS Yar, V Sharma, S Wakode , Archiv der Pharmazie – Chemistry in Life Sciences, 2017, 350, e1700146.

    2017
  37. 37.

    Synthesis, characterization and biological evaluation of 3-acetylindole derivatives as anti-microbial and antioxidant agents, H Kumar, S Wakode , A Kaur, The Pharma Innovation Journal, 2017, 6(5), 65-69.

    2017
  38. 38.

    Multiple sclerosis: an insight into experimental autoimmune encephalomyelitis (EAE), C Bakshi , S Wakode, World Journal of Pharmaceutical Sciences, 2017, 6,7, 459-476

    2017
  39. 39.

    Pharmacognostical evaluation and anthelmentic activity of Swertia alata Royle , S Bajaj, S Wakode , International Journal of Pharmaceutical Sciences and Research (IJPSR), 2017, 8(8), 3315-3324.

    2017
  40. 40.

    HPTLC analysis and antiproliferative effect of various extracts of Swertia alata on growth of Leishmania donovani Promastigotes In-vitro , S Bajaj, S Wakode , W Khan, Pharmacognosy Journal (PJ), 2017, 9(6), suppl: s107-s116.

    2017
  41. 41.

    Effect of extraction solvent on total phenol content, total flavonoid content, antioxidant and anti-inflammatory activity of Artabortrys hexapetalus , S Bajaj, S Wakode, International Journal Of Biology, Pharmacy And Allied Sciences, 2017, 6(8),1562-1577.

    2017
  42. 42.

    Evaluation of total phenolic, flavonoid, Invitro antioxidant potential and anti-inflammatory activity of successive extracts of Swertia alata , S Bajaj, S Wakode , Bulletin of environment pharmacology (BEPLS), 2017, 6(9), 73-81.

    2017
  43. 43.

    Synthesis, biological activity and recent advancement of benzothiazoles: a classical review, S Gulati, S Wakode , A Kaur, K Anand, World Journal Pharmacy And Pharmaceutical Science, 2017, 6(6), 1842-1869.

    2017
  44. 44.

    Transfersomes:A novel technique for Transdermal drug delivery, Y Malhotra, S Wakode . British Journal of Pharmaceutical and Medical Research, 2017, 2,492-501.

    2017
  45. 45.

    Development of drugs based on Benzimidazole Heterocycle: Recent advancement and insights, K Anand, S Wakode, International Journal of Chemical Studies, 2017, 5, 350-362

    2017
  46. 46.

    Biologically active Benzoxazole: A comprehensive review, N Aggarwal, A Kaur, K Anand, H Kumar, SR Wakode, International Journal of Pharmaceutical Science and Research, 2017, 2, 1-5.

    2017
  47. 47.

    Synthesis and pharmacological evaluation of Pyrazole derivatives containing Sulfonamide moiety, K Somakala, M Amir, V Sharma, S Wakode , Monatshefte für Chemie-Chemical, 2017,147, 2029.

    2017
  48. 48.

    Feronia Limonia-A Wonder Drug, H Amin, S Wakode , RK Tonk, World Journal of Pharmacy and Pharmaceutical Sciences, 2017, 6, 1982-1994.

    2017
  49. 49.

    Quality by design approach for analytical method development, S Sharma, S Wakode , World Journal of Pharmacy and Pharmaceutical Sciences, 2017, 6,354-368.

    2017
  50. 50.

    Imidazole synthesis and its biological activities, A review, P Manocha, S R Wakode , A Kaur, K Anand, H Kumar, International Journal of Pharmaceutical Science and Research, 2016, 1,12-16.

    2016
  51. 51.

    Pharmacophore generation and atom based 3D-QSAR of quinoline derivatives as selective phosphodiesterase 4B inhibitors, V Sharma, S Wakode , RSC advances, 2016, 6, 75805

    2016
  52. 52.

    Antimicrobial Properties of Benzimidazole and Mannich Bases of Benzimidazole: A Review, P Kaur, SR Wakode , International Journal of Science and Research, 2016, 5, 762-772.

    2016
  53. 53.

    Synthesis and in vitro evaluation of Anticancer activity of Mannich Bases of Benzimidazole derivatives, P Kaur, S Wakode , International Journal of Science and Research (IJSR), 2016, 5, 1096-1099.

    2016
  54. 54.

    Triterpinoids from the stem bark of Myrica Esculenta Buch. Ham , S Agnihotri, S Wakode , M Ali, World Journal of Pharmacy and Pharmaceutical Sciences, 2016, 5, 1319-1327.

    2016
  55. 55.

    Standardization of Artabortrys hexapetalus, S Bajaj, S Wakode , International Journal of Pharmacognosy and Phytochemical Research, 2016, 8, 398-406.

    2016
  56. 56.

    Recent Advances in the synthesis of isoquinoline and its analoue: A review, J Jacob, N Varghese, SP Rasheed, S Agnihotri, V Sharma, S Wakode, World Journal of Pharmacy and Pharmaceutical Sciences, 2016, 5, 1821-1837.

    2016
  57. 57.

    Pain: A review, H Kumar, S Wakode , T Arora, International Journal of Pharmaceutical Science and Research, 2016, I, 1-7.

    2016
  58. 58.

    Development and validation of a stability indicating HPTLC method for estimation of Canagliflozin in bulk and pharmaceutical dosage form, I Kaur, S Wakode , HP Singh, Journal of Applied Pharmaceutical Science , 2016, 6, 51-57

    2016
  59. 59.

    Development and validation of a stability indicating UV spectroscopic method for determination of Canagliflozin in bulk and pharmaceutical dosage form, I Kaur, S Wakode , HP Singh, Pharmaceutical Methods, 2016, 7, 63-69.

    2016
  60. 60.

    Development and validation of a stability indicating Reverse Phase HPLC-PDA method for determination of Canagliflozin in bulk and pharmaceutical dosage form, I Kaur, S Wakode , HP Singh, S Manchanda, Pharmaceutical Methods, 2016, 7, 54-62

    2016
  61. 61.

    Development and validation of UV spectroscopic method for determination of Canagliflozin in bulk and pharmaceutical dosage form, I Kaur , S Wakode , HP Singh , Pharmaceutical Methods, 2015, 6, 82-86.

    2015
  62. 62.

    Benzoxazole: The molecule of diverse pharmacological importance, A Kaur, S Wakode , DP Pathak, International Journal of Pharmacy and Pharmaceutical Sciences, 2014, 7, 1.

    2014
  63. 63.

    Validated UV spectrophotometric method for estimation of Tolnaftet, AK Sarawal, S Wakode , Indian Research Journal of Pharmacy and Science, 2014, 1, 23-30.

    2014
  64. 64.

    Development and validation of UV visible spectrophotometric method for the estimation of Flupiritine maleate in bulk drug and Phrmaceutical dosage form, D Patel, S Wakode , Indian Research Journal of Pharmacy and Science, 2014, 1, 31-37.

    2014
  65. 65.

    Synthesis, characterization and evaluation of antimicrobial activity of various Mannich bases of Isoindoledione derivatives, P Chakrawarti, S Wakode , International Journal of Science and Resesarch, 2013, 4, 2624-2628.

    2013
  66. 66.

    Synthesis and characterization of 3-acetylindole derivatives and evaluation of their anti-inflammatory and antimicrobial activity, L Verma, S Wakode , The Pharma Innovation, 2013, 2, 41-92.

    2013
  67. 67.

    Synthesis through microwave irradiation, characterization and evaluation of antimicrobial activity of 2-phenyl-1, 3-Benzoxazole derivatives, T Sana, S Wakode . International Research Journal of Pharmacy, 2012, 3, 213-217.

    2012
  68. 68.

    Indazole: A medicinally important heterocyclic moiety, A Thangadurai, M Minu, S Wakode , S Agrawal,, B Narasimhan, Medicinal Chemistry Research, 2012, 21, 269.

    2012
  69. 69.

    Chemical composition, antimicrobial and topical anti-inflammatory activity of essential oil of Amomum subulatum fruits, S Agnihotri, S Wakode , M Ali, Acta Poloniae Pharmaceutica – Drug Research, 2012, 69, 1177-1181.

    2012
  70. 70.

    Essential oil of Myrica esculenta Buch. Ham.: Composition, antimicrobial and topical anti-inflammatory activity, S Agnihotri, S Wakode , M Ali, Natural Product Research, 2012, 26, 2266.

    2012
  71. 71.

    Synthesis of some Benzimidazole derivatives & evaluation of their antimicrobial activity, AS Kohli, SR Wakode , International Journal of Pharmaceutical Frontier Research, 2012, 2, 56-57.

    2012
  72. 72.

    Biological value of the heterocyclic compound quinazoline, A Thangadurai, M Minu, S Wakode , S Agrawal, U Kulandaivelu, B Narasimhan, Acta Pharmaceutica Sciencia , 2011, 53, 347.

    2011
  73. 73.

    Structure based rational drug design of Selective phosphodiesterase-4 ligands as Anti-inflammatory molecules, V Sharma, S Wakode , V Lather, R Mathur, MX Fernandes, Bulletin of Pharmaceutical Research, 2011, 1, 33.

    2011
  74. 74.

    Chemical composition, antimicrobial and topical anti-inflammatory activity of Valeriana jatamansi Jones. Essential oil, S Agnihotri, S Wakode , M Ali, Journal of Essential Oil Bearing Plants, 2011, 14, 417.

    2011
  75. 75.

    An overview on anti-inflammatory properties and chemo-profiles of plants used in traditional medicine, S Agnihotri, S Wakode , A Agnihotri, Indian Journal of Natural Products and Resources, 2010, 1, 150.

    2010
  76. 76.

    Development and validation of a UV spectrophotometric method for the estimation of torsemide in bulk and in tablet dosage form, J Gupta, G Kanojia, V Yadav, SR Wakode , Journal of Chemical and Pharmaceutical Research, 2010, 2, 513.

    2010
  77. 77.

    Antimicrobial Potential of Adhatoda vasaka (L.) Nees, S Agnihotri, S Wakode, Indian Drugs, 2010, 47, 61.

    2010
  78. 78.

    Antimicrobial activity of essential oil and various extracts of fruits of Greater Cardamom, S Agnihotri, S Wakode , Indian Journal of Pharmaceutical Sciences, 2010, 75, 657.

    2010
  79. 79.

    Synthesis, antimicrobial activity and QSAR studies of new 2, 3-disubstituted-3, 3a, 4, 5, 6,7-hexahydro-2H–indazoles., M Minu, SS Agrawal , SR Wakode , A. Thangadurai, B. Narasimhan. Bioorganic& Medicinal Chemistry Letters, 2009, 19, 2960.

    2009
  80. 80.

    3,4-Disubstituted-1,2,3,4,5,6,7,8-octahydroquinazoline-2-thiones: Synthesis, antimicrobial evaluation and QSAR investigations using Hansch analysis, M Minu, SS Agrawal , SR Wakode , A. Thangadurai, B. Narasimhan, Archiv der Pharmazie – Chemistry in Life Sciences, 2008, 431, 231.

    2008
  81. 81.

    QSAR Analysis of N-alkyl imidazole Analogs as Antibacterial Agent, N Khan, LK Soni, AK Gupta, SR Wakode, RD Wagh, SG Kaskhedikar, Indian Journal of Pharmaceutical Sciences , 2006, 68, 341.

    2006
  82. 82.

    Development of Pharmacophoric Model of Condensed Pyridine and Pyrimidine Analogs as HMG-CoA Reductase Inhibitors, M Saxena, LK Soni, AK Gupta , SR Wakode , AK Saxena, SG Kaskhedikar , Indian Journal of Biochemistry and Biophysics, 2006, 43, 32.

    2006
  83. 83.

    Role of Gut Microbiota and Probiotic in Chronic Fatigue Syndrome 9 Anjali Sharma, Sharad Wakode , Supriya Sharma, and Faizana Fayaz, Probiotic Research in Therapeutics, P. K. Deol, S. K. Sandhu (eds.), Springer Nature Singapore Pte Ltd. 2022 https://doi.org/10.1007/978-981-16-6760-2_9

    2022
  84. 84.

    Polymer-Based Nanoplatforms for Targeting Breast Cancer, RS Tade, PO Patil, SN Nangare, AG Patil, MP More, PK Deshmuk, S Wakode, S B Bari et al. Polymeric nanoparticles for the treatment of solid tumors, 2022,373-400.

    2022

Membership of Important Committees & Professional Associations

  • Member, Academic Council, Delhi Pharmaceutical Science & Research University (DPSRU)

  • Member, University Research Advisory Committee (URAC), DPSRU

  • Ex. Member Secretary, IAEC (Institutional Animal Ethics Committee), DIPSAR

  • Board of Studies member - Dept of Pharmacy, Central University of Rajasthan

  • Board of Studies member - Dept of Pharmacy, Indira Gandhi Tribal University, Amarkantak (MP)

  • Board of Studies member - Dept of Pharmacy, Guru Jambeshwar University, Hissar, Haryana

  • Board of Studies member - Dept of Pharmaceutical Sciences, Indira Gandhi University, Meerpur, Haryana

  • Board of Studies member - Faculty of Pharmacy, Jaipur National University, Jaipur, Rajasthan

  • Ex-Member, Board of Research Studies, Delhi University

  • Ex-Board of Studies member - Lachoo Memorial College of Science and Technology, Jodhpur

Professional Contributions

  • Expert for Pharmacy Council of India, AICTE, National Board of Examinations and other Government agencies

  • PhD/M.Pharm Examiner for Jamia Hamdard, Nagpur, Pune, BITS Pilani, IIT-Delhi, MD University Rohtak and 10+ universities

  • Expert in Selection Committees for CCRHC, DSSB (DIPSAR), DTE

  • Expert for inspection of drug testing laboratories by Ministry of Health, Govt. of India and GMSD, New Delhi

  • Coordinator of XXII Quality Improvement Program at DIPSAR

  • Member Scientific services committee in 53rd Indian Pharmaceutical Congress, New Delhi (2001)