Dr. Kalicharan Sharma
Assistant Professor
School of Pharmaceutical Sciences (SPS)
Google ScholarScopus ProfileEducational Qualifications
M. Pharm , Ph.D.
Area of Specialization / Research
Molecular Modelling and Biological evaluation of antiviral agents and their optimization.
Notable Publications
- 1.
Mymoona, A.; Kalicharan, Sharma .; Alam, M. M.; Zaman, M. S.; Husain, A.; Shakir, A.; Shah, A. K. Current Enzyme Inhibition 2014, 10 , 98. IF:0.40
2014 - 2.
Hameed, A. D.; Ovais, S.; Yaseen, R.; Rathore, P.; Samim, M.; Singh, S.; Sharma, Kalicharan .; Akhtar, M.; Javed, K. Archiv der Pharmazie 2016 . IF: 3.75
2016 - 3.
Tantray, M. A.; Khan, I; Alam, S. M.; Umar, S.; Ali, Y.; Sharma, Kalicharan . Hamid, H. Chemical Biology and Drug Design 2016 . IF: 2.87
2016 - 4.
Yaseen, Raed; Pushpalatha, H.; Reddy, G. Bhanuprakash; Ismael, Ameer; Ahmed, Ayad; Hameed, Alhamzah Dh.; Ovais, Syed; Rathore, Pooja; Samim, Mohammad; Akhtar, Mymoona; Sharma, Kalicharan ; Shafi, Syed; Singh, Surender; javed, kalim; Journal of Enzyme Inhibition and Medicinal Chemistry IF: 4.31
- 5.
Ismail, T.; Shafi, S.; Singh, S.; Sidiq, T.; Khajuria, A.; Rouf, A.; Yadav, M.; Saikam, V.; Singh, P. P.; Alam, M. S.; Islam, N.; Sharma, Kalicharan .; Sampath Kumar, H. M. European journal of medicinal chemistry 2016 . IF: 6.51
2016 - 6.
Shafi, S.; Afrin, F.; Islamuddin, M.; Chouhan, G.; Ali, I.; Naaz, F.; Sharma, Kalicharan .; Zaman, M. S., beta-Nitrostyrenes as Potential Anti-leishmanial Agents. Frontiers in microbiology 2016, 7 , 1379. IF: 5.64
2016 - 7.
Kumar, V.; Bhatt, P. C.; Sharma, Kalicharan .; Rahman, M.; Patel, D. K.; Sethi, N.; Kumar, A.; Sachan, N. K.; Kaithwas, G.; Al-abbasi, F. A.; Anwar, F.; Verma, A. BMC Complementary and Alternative Medicine 2016 , 16 , 510. IF: 3.65
2016 - 8.
Chanda, R.; Mymoona, A.; Kalicharan, Sharma .; Jagdish, K.; Anees Ahmad, S.; Gita, C. Letters in Drug Design & Discovery 2017 , 14 , 1. IF: 1.15
2017 - 9.
Sharma, Kalicharan .; Shrivastava, A.; Mehra, R. N.; Deora, G. S.; Alam, M. M.; Zaman, M. S.; Akhter, M. Archiv der Pharmazie 2018 , 351 . IF: 3.75
2018 - 10.
Kumar, V.; Sharma, Kalicharan .; Ahmed, B.; Al-Abbasi, F. A.; Anwar, F.; Verma, A. RSC Advances 2018 , 8 , 18180. IF: 3.36
2018 - 11.
Kalicharan, Sharma .; Apeksha, S.; Pooja, T.; Shweta, S.; Mohammad, S.; Alam, M. M.; Mymoona, A. Letters in Drug Design & Discovery 2018 , 15 , 1. IF: 1.15
2018 - 12.
Sharma, Kalicharan .; Tanwar, O.; Sharma, S.; Ali, S.; Alam, M. M.; Zaman, M. S.; Akhter, M. Bioorganic Chemistry 2018 . IF: 5.41
2018 - 13.
Iqubal, A.; Sharma, S.; Sharma, Kalicharan .; Bhavsar, A.; Hussain, I.; Iqubal, M. K.; Kumar, R. Life Sciences 2018 . IF: 5.03
2018 - 14.
Pathak, A.; Rohilla, A.; Gupta, T.; Akhtar, M. J.; Haider, M. R.; Sharma, Kalicharan .; Haider, K.; ShaharYar, M. European Journal of Medicinal Chemistry 2018 . IF: 6.51
2018 - 15.
Pratap, S.; Naaz, F.; Reddy, S.; Jha, K. K.; Sharma, Kalicharan .; Sahal, D.; Akhter, M.; Nayakanti, D.; Kumar, H. M. S.; , V.; Pandey, K.; Shafi, S., Archiv der Pharmazie 2019, 352 (1), 1800192. IF: 3.75
2019 - 16.
Sharma, Kalicharan .; Tanwar, O.; Deora, G. S.; Ali, S.; Alam, M. M.; Zaman, M. S.; Krishna, V. S.; Sriram, D.; Akhter, M., Bioorganic & Medicinal Chemistry 2019, 27 (7), 1421-1429. IF: 3.64
2019 - 17.
Hassan, N.; Singh, M.; Sulaiman, S.; Jain, P.; Sharma, Kalicharan .; Nandy, S.; Dudeja, M.; Ali, A.; Iqbal, Z., ACS Omega 2019, 4 (5), 9583-9592. IF: 3.51
2019 - 18.
Mohapatra, S.; Asfer, M.; Anwar, M.; Sharma, Kalicharan .; Akhter, M.; Ahmad, F. J.; Siddiqui, A. A., Heliyon 2019, 5 (6), e01955. IF: 2.85
2019 - 19.
Rahman, M.; Al-Ghamdi, S. A.; Alharbi, K. S.; Beg, S.; Sharma, Kalicharan .; Anwar, F.; Al-Abbasi, F. A.; Kumar, V. Drug Delivery 2019 , 26 (1), 782-793. IF: 3.09
2019 - 20.
Sharma, Kalicharan .; Neshat, N.; Sharma, S.; Giri, N.; Srivastava, A.; Almalki, F.; Saifullah, K.; Alam, M. M.; Shaquiquzzaman, M.; Akhter, M., Archiv der Pharmazie n/a (n/a), e1900287. IF: 3.75
- 21.
Ramesh K. Goyal, J. M., Rajiv Tonk, Mahaveer Dhobi, Bhoomika Patel, Kalicharan Sharma , Subbu Apparsundaram, Reviews in Cardiovascular Medicine 2020, 21 (3), 365-384. IF: 2.93
2020 - 22.
Kumar PA, Das S, Mohapatra S, Basu SP, Sharma K , Sharma M, Singh AP. J Appl Pharm Sci, 2020; 10(08):139-144. IF: 1.32
2020 - 23.
Kumar, V.; Sachan, R.; Rahman, M.; Sharma, K.; Al-Abbasi, F. A.; Anwar, F., Journal of Biomolecular Structure and Dynamics 2020, 1-15. IF: 3.54
2020 - 24.
Bansal, P.; Bhandari, U.; Sharma, K.; Arya, P., Human & Experimental Toxicology 2021, 40 (1), 60-70. IF: 3.01
2021 - 25.
Kumar, V.; Sachan, R.; Rahman, M.; Rub, R. A.; Patel, D. K.; Sharma, K.; Gahtori, P.; Al-abbasi, F. A.; Alhayyani, S.; Anwar, F.; Kim, H. S., Biomedicine & Pharmacotherapy 2021, 137 , 111298. IF: 6.52
2021 - 26.
Acharya, A.; Pandey, K.; Thurman, M.; Klug, E.; Trivedi, J.; Sharma, K.; Lorson, C. L.; Singh, K.; Byrareddy, S. N.; Gallagher, T., Discovery and Evaluation of Entry Inhibitors for SARS-CoV-2 and Its Emerging Variants. Journal of Virology 2021, 95 (24), e01437-21. IF: 4.50
2021 - 27.
Naaz, F.; Ahmad, F.; Lone, B. A.; Khan, A.; Sharma, K.; IntzarAli; ShaharYar, M.; Pokharel, Y. R.; Shafi, S., Apoptosis Inducing 1,3,4-Oxadiazole Conjugates of Capsaicin: Their In Vitro Antiproliferative and In Silico Studies. ACS Medicinal Chemistry Letters 2021, 12 (11), 1694-1702. IF: 4.34
2021 - 28.
Kannan SR, Spratt AN, Sharma K, Chand HS, Byrareddy SN, Singh K. Omicron SARS-CoV-2 variant: Unique features and their impact on pre-existing antibodies. Journal of Autoimmunity. 2022 2022/01/01/; 126:102779. IF: 14.56
2022 - 29.
Khan I, Tantray MA, Hamid H, Sarwar Alam M, Sharma K, Kesharwani P. Design, synthesis, in vitro antiproliferative evaluation and GSK-3β kinase inhibition of a new series of pyrimidin-4-one based amide conjugates. Bioorganic Chemistry. 2021 2021/11/26/:105512. IF: 5.275
2021 - 30.
Saathvik R. Kannan, Austin N. Spratt, Kalicharan Sharma, Ramesh Goyal, Anders Sön-nerborg, Subbu Apparsundaram, Christian L. Lorson, Siddappa N. Byrareddy and Kamal Singh., Complex Mutation Pattern of Omicron BA.2: Evading Antibodies without Losing Receptor Interactions. International Journal of Molecular Science. 2022, 23. IF: 5.946
2022 - 31.
Gupta, M.; Sharma, V.; Sharma, K.; Kumar, A.; Sharma, A.; Kazmi, I.; Al-Abbasi, F. A.; Alzarea, S. I.; Afzal, O.; Altamimi, A. S. A.; Singh, S. K.; Gupta, G.; Paudel, K. R.; Hansbro, P. M.; Dua, K., A kNGR Peptide-Tethered Lipid–Polymer Hybrid Nanocarrier-Based Synergistic Approach for Effective Tumor Therapy: Development, Characterization, Ex-Vivo, and In-Vivo Assessment. Pharmaceutics 2022, 14 (7), 1401. IF: 6.526
2022 - 32.
Yadav, V.; Reang, J.; Sharma, V.; Majeed, J.; Sharma, P. C.; Sharma, K.; Giri, N.; Kumar, A.; Tonk, R. K., Quinoline-derivatives as privileged scaffolds for medicinal and pharmaceutical chemists: A comprehensive review. Chemical Biology & Drug Design 2022, 100 (3), 389-418. IF: 2.87
2022 - 33.
Aasim; Sharma, R.; Patil, C. R.; Kumar, A.; Sharma, K., Identification of vaccine candidate against Omicron variant of SARS-CoV-2 using immunoinformatic approaches. In Silico Pharmacology 2022, 10 (1), 12. IF: 2.12
2022 - 34.
Arya, P.; Bhandari, U.; Sharma, K.; Bansal, P., Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway. Iranian Journal of Basic Medical Sciences 2022, 25 (5), 577-585. IF: 2.69
2022 - 35.
Spratt, A. N.; Kannan, S. R.; Sharma, K.; Sachdev, S.; Kandasamy, S. L.; Sönnerborg, A.; Lorson, C. L.; Singh, K., Continued Complexity of Mutations in Omicron Sublineages. Biomedicines 2022, 10 (10), 2593. IF: 4.75
2022 - 36.
Sharma, S.; Ansari, M. H. R.; Sharma, K.; Singh, R. K.; Ali, S.; Alam, M. M.; Zaman, M. S.; Alam, P.; Akhter, M., Pyrazoline scaffold: hit identification to lead synthesis and biological evaluation as antidiabetic agents. Future Medicinal Chemistry 2023, 15 (1), 9-24. IF: 4.76
2023 - 37.
Ramzan, F.; Nabi, S. A.; Lone, M. S.; Imtiyaz, K.; Urooj, L.; Vishakha, V.; Sharma, K.; Rizvi, M. M. A.; Shafi, S.; Samim, M.; Bano, S.; Javed, K., Synthesis, Molecular Docking, and Biological Evaluation of a New Series of Benzothiazinones and Their Benzothiazinyl Acetate Derivatives as Anticancer Agents against MCF-7 Human Breast Cancer Cells and as Anti-Inflammatory Agents. ACS Omega 2023 . IF: 4.13
2023 - 38.
Kumar, V.; Sharma, K.; Sachan, R.; Alhayyani, S.; Al-abbasi, F. A.; Singh, R.; Anwar, F., Co-drug development of gallic acid and metformin targeting the pro-inflammatory cytokines for the treatment of breast cancer. Journal of Biochemical and Molecular Toxicology n/a (n/a), e23300. IF: 3.56
- 39.
Karande, S.; Sharma, K.; Kumar, A.; Charan, S.; Patil, C.; Sharma, A., Potential role of biopeptides in the treatment of idiopathic pulmonary fibrosis. Health Sciences Review 2023, 6 , 100081. IF: 00
2023 - 40.
Hassan, N.; Farooq, U.; Das, A. K.; Sharma, K.; Mirza, M. A.; Fatima, S.; Singh, O.; Ansari, M. J.; Ali, A.; Iqbal, Z., In Silico Guided Nanoformulation Strategy for Circumvention of Candida albicans Biofilm for Effective Therapy of Candidal Vulvovaginitis. ACS Omega 2023 . IF: 4.13
2023 - 41.
Reang, J.; Sharma, K.; Sharma, P. C.; Yadav, V.; Sharma, V.; Majeed, J., Discovery of VEGFR inhibitors through virtual screening and energy assessment. Journal of Biochemical and Molecular Toxicology n/a (n/a), e23321. IF: 3.56
- 42.
Suri, R.; Nag, T. C.; Mehra, N.; Neupane, Y. R.; Shafi, S.; Sharma, D.; Sharma, K.; Sultana, Y.; Kohli, K., Sirolimus loaded chitosan functionalized PLGA nanoparticles protect against sodium iodate-induced retinal degeneration. Journal of Drug Delivery Science and Technology 2023, 82 , 104369. IF: 5.07
2023 - 43.
Kajol; Yadav, V.; Reang, J.; Sharma, K.; Tonk, K. R.; Jain, P.; Verma, S., Overview of the Current Advancements and Trends in the Transungual Drug Delivery System. Letters in Drug Design & Discovery 2023, 20 , 1-1. IF: 1.11
2023 - 44.
Ramzan, F.; Nabi, S. A.; Lone, M. S.; Bonardi, A.; Hamid, A.; Bano, S.; Sharma, K.; Shafi, S.; Samim, M.; Javed, K.; Supran, C. T., Synthesis, biological evaluation and theoretical studies of (E)-1-(4-sulfamoyl-phenylethyl)-3-arylidene-5-aryl-1H-pyrrol-2(3H)-ones as human carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 2023, 38 (1), 2189126. IF: 4.31
2023 - 45.
Sharma, S.; Iqubal, A.; Khan, V.; Sharma, K.; Najmi, A. K.; Haque, S. E., Icariin ameliorates oxidative stress-induced inflammation, apoptosis, and heart failure in isoproterenol-challenged Wistar rats. Iranian journal of basic medical sciences 2023, 26 (5), 517-525. IF: 2.69
2023 - 46.
Agarwal, U.; Tonk, K. R.; Sharma, K.; Bhutani, R.; Verma, S., Synthesis, ADME, Molecular Docking, and Biological Evaluation of New 2-Aminobenzothiazloes. Current Bioactive Compounds 2023, 19 , 1-1. IF: 1.11
2023 - 47.
Rai, Santosh Kumar, Patil, Rakesh Iswar, Roy, Somnath Singha, Sharma , Kalicharan , Dwivedi, Rahul, Bapuram, Srinivasa Reddy, Kumar, Anil., “Novel apoptosis signal regulation kinase inhibitors”, Assignee: Mankind Pharma Ltd., India, Pub No. US 2022/0332700 A1, Grant date 20/10/2022 .
2022 - 48.
Reang, J.; Yadav, V.; Vinita; Majeed, J.; Sharma, P. C.; Tonk, R. K.; Sharma, K., Informatics: Tools and Databases in Drug Discovery. In CADD and Informatics in Drug Discovery , Rudrapal, M.; Khan, J., Eds. Springer Nature Singapore: Singapore, 2023; pp 53-77.
2023 - 49.
Majeed, J.; Reang, J.; Sharma, K.; Acharya, P. C.; Chander Sharma, P., Chapter 12 – Antiamoebic drugs. In Medicinal Chemistry of Chemotherapeutic Agents , Acharya, P. C.; Kurosu, M., Eds. Academic Press: 2023; pp 397-429.
2023 - 50.
Sharma, P.; Sharma, K.; Nandave, M., Chapter 2 – Computational approaches in drug discovery and design. In Computational Approaches in Drug Discovery, Development and Systems Pharmacology , Gautam, R. K.; Kamal, M. A.; Mittal, P., Eds. Academic Press: 2023; pp 53-93.
2023
Awards & Achievements
Outstanding Researcher Award-2022, DPSRU, New Delhi
Contributed to Coroquil-Zn formulation for SARS-CoV-2 (currently marketed as immunomodulator)
MKP10241 antidiabetic compound (co-designed) in Phase-I clinical trial
3rd prize at International Symposium Young Innovator Choice Competition, ICT Mumbai (2011)
3rd prize at National Conference on Medical Informatics 2014 at AIIMS New Delhi (2015)
H-Index: 15, I-10 Index: 19, 40+ peer-reviewed publications
Book Chapters
- 1.
Resource Person in Innovation conclav-2022
2022 - 2.
Got the third prize in International Symposium on “ Young innovator choice competition ” being organized by Institute of Chemical Technology, Mumbai-2011.
2011 - 3.
Participated in 65 th India Pharmaceutical Congress being organised by Amity University, Noida-2013.
2013 - 4.
Got the third prize in international conference “National Conference on Medical Informatics 2014” organised by AIIMS New Delhi-2015.
2014 - 5.
Delivered an invited hands on training in “Drug Designing and Applications of Machine Learning” organized by Manav Rachna Manav Rachna University, Faridabad-2018.
2018 - 6.
Invited as “Resource Person” at the “Innovation Conclave-22” organised by Jamia Hamdard-2022.
2022
Paper / Poster Presentations
- 1.
Resource Person in Innovation conclav-2022
2022 - 2.
Got the third prize in International Symposium on “ Young innovator choice competition ” being organized by Institute of Chemical Technology, Mumbai-2011.
2011 - 3.
Participated in 65 th India Pharmaceutical Congress being organised by Amity University, Noida-2013.
2013 - 4.
Got the third prize in international conference “National Conference on Medical Informatics 2014” organised by AIIMS New Delhi-2015.
2014 - 5.
Delivered an invited hands on training in “Drug Designing and Applications of Machine Learning” organized by Manav Rachna Manav Rachna University, Faridabad-2018.
2018 - 6.
Invited as “Resource Person” at the “Innovation Conclave-22” organised by Jamia Hamdard-2022.
2022
Patents
- 1.
Novel apoptosis signal regulation kinase inhibitors - US 2022/0332700 A1
2022
