Dr. Atul Jain

Assistant Professor

DIPSAR

atuljain@dpsru.edu.in

Google Scholar Scopus Profile

ORCID: 0000-0003-2511-3856

Educational Qualifications

M. Pharm, Ph.D(Pharmaceutics)

Area of Specialization / Research

Quality by design (Qbd)-driven development of nanostructured drug delivery systems, Lipomer, Conjugation, Receptor mediated drug delivery systems, Bioavailability enhancement of poorly

Notable Publications

1.
Chand P, Kumar H, Jain R, Jain A, Jain V. Flavonoids: As omnipotent candidates for cancer management. South African Journal of Botany. 2023; 158:334-46.
2023
2.
Pant A, Sharma G, Saini S, Jain A, Barnwal RP, Singh G, et al. Quality by Design (QbD)‐Steered Development and Validation of Analytical and Bioanalytical Methods for Raloxifene: Application of Monte Carlo Simulations and Variance Inflation Factor. Biomedical Chromatography. 2023: e5641.
2023
3.
Kumari A, Raina N, Wahi A, Goh KW, Sharma P, Nagpal R, et al. Wound-Healing Effects of Curcumin and Its Nanoformulations: A Comprehensive Review. Pharmaceutics. 2022;14(11):2288.
2022
4.
Kumar D, Singh H, Jain A, Sharma V, Bhardwaj N, Puri S, et al. Response surface methodology for removal of copper (II) ions from aqueous solutions by DMSA@ SiO2@ Fe3O4 nanocomposite. Chemical Papers. 2023;77(4):1907-20.
2023
5.
D. Kumar, H. Singh, A. Jain, V. Sharma, N. Bharadwaj, S. Puri, M. Khatri. Response surface methodology for removal of copper ions from aueous solution by DMSA@SiO2@Fe3O4 nanocomposite. Chemical Papers, 2022 IF 2.2
2022
6.
A. Kumari, N. Raina, A. Wahi, K. W. Goh, P. Sharma , R. Nagpal, A. Jain, L. C. Ming, M. Gupta.Wound-Healing Effects of Curcumin and Its Nanoformulations: A Comprehensive Review. Pharmaceutics, 2022, IF 6. 29
2022
7.
S. Saini, T. Sharma, A. Jain, H. Kaur, O. P. Katare, B. Singh. Systematically designed chitosan-coated solid lipid nanoparticles of ferulic acid for effective management of Alzheimer’s Disease: A Preclinical Evidence. Colloids Surf B Biointerfaces. 2021, IF 5.268 , ISSN No 09277765, DOI: 10.1016/j.colsurfb.2021.111838
2021
8.
A. Jain, T. Sharma, R. Kumar, O.P Katare, B. Singh. Raloxifene-loaded SLNs with enhanced biopharmaceutical potential: QbD steered development, in vitro evaluation, in vivo pharmacokinetics and IVIVC. Drug Deliv Trans Res 2021. IF 4.6 , ISSN No 21903948, DOI: 10.1007/s13346-021-00990-x
2021
9.
H. Singh, A. Jain, J. Kaur, S. K. Arya, M. Khatri. Adsorptive removal of oil from water using SPIONs–chitosan nanocomposite: Kinetics and process optimization. Appl. Nanosci. 2020,10:1281-1295. IF 3.674, ISSN 2190-5517, DOI: 10.1007/s13204-019-01195-y
2020
10.
M. Kaurav, R. Kumar,A. Jain,R. S. Pandey. Novel biomimetic reconstituted built-in adjuvanted Hepatitis B vaccine for transcutaneous immunization. 2019, J. Pharma Sci, 108, , 3550-3559. IF 3.43, ISSN 1520-6017, DOI: 10.1016/j.xphs.2019.07.007
2019
11.
T. Sharma, O. P. Katare, A. Jain, S. Jain, D. Chaudhari, B. Borges, B. Bhoop. QbD-steered development of biotin-conjugated nanostructured lipid carriers for oral delivery of chrysin: role of surface modification in improving biopharmaceutical performance. Colloids Surf B Biointerfaces. 2021; 197:111429. IF 5.268 , ISSN No 09277765, DOI: 10.1016/j.colsurfb.2020.111429
2021
12.
T. Sharma, A. Jain, S. Saini, O.P. Katare and B. Singh. Implementation of analytical quality‐by‐design and green analytical chemistry approaches for the development of robust and ecofriendly UHPLC analytical method for quantification of chrysin. Sep. Sci. Plus, 2020,3:384-398 IF- NA, ISSN No 2573-1815, DOI: 10.1002/sscp.202000028
2020
13.
T Sharma, S Saini, A Jain, R Kaur B Singh. Developing Lipidic Nanocarriers using formulation by design (FbD), Spinco Biotech Cutting Edge, February 2020 IF-NA, ISSN-NA
2020
14.
B. Singh, T Sharma, R. Kaur, S. Saini, A. Jain, S. Beg, K. Raza and B. Singh Systematic development of drug nanocargos using formulation by design (FbD): An updated overview. Crit Rev Ther Drug Carrier Syst.2020, 37(3):229–269. IF 4.74 , ISSN 07434863, DOI: 10.1615/CritRevTherDrugCarrierSyst.2020032040
2020
15.
A. Jain, T. Sharma, S. Saini, O. P. Katare, V. Soni and B. Singh Nanocargoes: A burgeoning quest in cancer management. Curr. Nanomed. 2020,10 (2):149- 163. IF- NA, ISSN 2468-1881, DOI: 10.2174/2468187309666190823160241
2020
16.
T. Sharma, A. Jain, S. Saini, O.P. Katare, B. Singh. Supersaturated LFCS type III self-emulsifying delivery systems of sorafenib tosylate with improved biopharmaceutical performance: QbD-enabled development and evaluation. Drug Deliv.Transl. Res. 2020,10:839–861. IF 4.6 , ISSN 21903948, DOI: 10.1007/s13346-020-00772-x
2020
17.
S. Beg, S. Dhiman, T Sharma, A. Jain, R. K. Sharma, A. Jain and B. Singh. Stimuli responsive in situ gelling systems loaded with PLGA nanoparticles of moxifloxacin hydrochloride for effective treatment of periodontitis. AAPS PharmSciTech. 2020,21(3):76. IF 3.246, ISSN No-1530-9932, DOI 10.1208/s12249-019-1613-7
2020
18.
S. Saini, T. Sharma, R. Kaur, A. Jain and B. Singh. Nanocountered lipid-based drug delivery strategies for crossing blood brain barrier in neurodegenerartion disorder. The Pharma Review. 2019,27-32. IF-NA, ISSN No – 0973-399X
2019
19.
A. Jain, S. Saini, R Kumar, T. Sharma, R. Swami, O. P. Katare and B. Singh. Phospholipid-based complex of raloxifene with enhanced biopharmaceutical potential: Synthesis, characterization and preclinical assessment. Int J Pharm. 2019, 571, 118698. IF 5.875 ISSN No-0378-5173
2019
20.
A. Jain, T. Sharma, G Sharma, R. K. Khurana, O. P. Katare and B. Singh. QbD-driven analytical method development and validation for raloxifene hydrochloride in pure drug and solid oral dosage form. 2019, Anal Chem. Lett. 2019, 9, 463-477. IF , ISSN No-2230-7532
2019
21.
A. Jain, S. Beg, S. Saini, T. Sharma, O.P. Katare and B. Singh. Application of chemometric approach for QbD-Enabled development and validation of an RP-HPLC method for estimation of methotrexate. J Liq Chromatogr Relat Technol, 2019,1-11. IF 1.312 , ISSN No – 1520572X
2019
22.
Parmar, A. Jain, S. Uppal, S.K. Mehta, K. Kaur, B. Singh, R. Sandhir and S. Sharma. Anti-proliferate and apoptosis triggering potential of methotrexate-transferrin conjugate encapsulated PLGA nanoparticles with enhanced cellular uptake by high affinity folate receptors. Artif Cells Nanomed Biotechnol.2018, 46:704-719. IF 5.678 , ISSN No – 2169-141X
2018
23.
A. Jain, R. Kaur, S. Beg, V. Kushwah, S. Jain and B. Singh. Novel cationic supersaturable nanomicellar systems of raloxifene hydrochloride with enhanced biopharmaceutical attributes. Drug Deliv Trans Res.2018, 8: 670-692. IF 4.6 , ISSN No – 21903948
2018
24.
A. Jain, G. Sharma, V. Kushwah, G. Ghoshal, A. Jain, B. Singh, US Shivhare, S Jain, O. P. Katare. Beta carotene-loaded zein nanoparticles to improve the biopharmaceutical attributes and to abolish the toxicity of methotrexate: a preclinical study for breast cancer. Artif Cells Nanomed Biotechnol. 2018, 46:402-412. IF 5.678 , ISSN No – 2169-141X
2018
25.
R. K. Khurana, A. Jain, A. Jain, T Sharma, B. Singh and P. Kesharwani. Administration of antioxidants in cancer: Debate of the decade. Drug Discov Today. 2018, 23:763-770. IF 7.851, ISSN No – 18785832
2018
26.
T. Sharma, R.K. Khurana, A. Jain, O. P. Katare and B. Singh. Development of a validated liquid chromatographic method for quantification of sorafenib tosylate in the presence of stress-induced degradation products and in biological matrix employing analytical quality by design (AqbD) approach. Biomed Chromatogr. 2018, 32:e4169. IF 1.902 , ISSN No – 10990801
2018
27.
P. Kesharwani, A. Jain, A. Jain, A.K. Jain, N.K. Garg, R.K. Tekade, R.R.S. Thakur and A. K. Iyer. Cationic bovine serum albumin (CBA) conjugated PLGA nanoparticles for extended delivery of methotrexate into brain tumor. RSC Adv. 2016, 6, 89040-89050. IF 3.361 , ISSN No – 2046-2069
2016
28.
A. Jain, A. Jain, P. Parajuli, V. Mishra, G. Ghoshal, B. Singh, U. S. Shivhare, O. P. Katare and P. Kesharwani. Recent advances in galactose-engineered nanocarriers for the site-specific delivery of siRNA and anticancer drugs. Drug Discov. Today. 2018,23:960-973. IF 7.851, ISSN No – 18785832
2018
29.
A. K, Jain, A. Jain, N.K. Garg, A. Agarwal, A. Jain, S.A. Jain, R.K. Tyagi, R.K. Jain, H. Agrawal and G.P. Agrawal. Adapalene loaded solid lipid nanoparticles gel: An effective approach for acne treatment. Colloids Surf B Biointerfaces. 2014,121:222-229. IF 5.268 , ISSN No 09277765
2014
30.
A. Jain, N.K. Garg, A. Jain, P. Kesharwani, A.K. Jain, P. Nirbhavane and R.K. Tyagi. A synergistic approach of adapalene-loaded nanostructured lipid carriers, and vitamin C co- administration for treating acne. Drug Dev Ind Pharm. 2016,42(6):897-905. IF 2.295, ISSN No – 03639045
2016
31.
A. Jain, P. Kesharwani, N.K. Garg, A. Jain, S.A Jain, A. K, Jain, P. Nirbhavane, R. Ghanghoria, R. K. Tyagi and O.P. Katare. Galactose engineered solid lipid nanoparticles for targeted delivery of doxorubicin. Colloids Surf B Biointerfaces. 2015,134:47-58. IF 5.268 , ISSN No 09277765
2015
32.
S. Beg, A. Jain, R. Kaur, S. S. Panda, O. P. Katare, B. Singh. QbD-driven development and validation of an efficient bioanalytical method for estimation of olmesartan medoxomil. J Chromatogr Sci Rel Tech. 2015,53:1048-1059. IF 1.312 , ISSN- 1520572X
2015
33.
A. Jain, P. Kesharwani, N. K.Garg, A. Jain, P. Nirbhavane, N. Dwivedi, S. Banerjee, A.K. Iyer and Iqbal Mohd Amin M. C. Nano-constructed carriers loaded with antioxidant: Boon for cardiovascular system. Curr Pharm Des. 2015,21(30):4456-64. IF 3.116 , ISSN 1381-6128
2015
34.
A. Jain, A. Jain, N. K. Garg, R. K. Tyagi, B. Singh, O. P. Katare, T. J. Webstere and V. Soni. Surface engineered polymeric nanocarriers mediate the delivery of transferrin–methotrexate conjugates for an improved understanding of brain cancer. Acta Biomater. 2015, 24: 140-151. IF 8.947 , ISSN 17427061
2015
35.
S. Beg, M. Rahman, A. Jain, S. Saini, P. Midoux, C. Pichon, F. Jalees Ahmad and S. Akhter. Nanoporous metal organic frameworks as hybrid polymer-metal composites for drug delivery and biomedical applications. Drug Discov. Today. 2017,22:625-637. IF 7.851, ISSN 18785832
2017
36.
A. Jain, A. Jain, N. K. Garg, R. K. Tyagi, B. Singh, O. P. Katare, T. J. Webstere and V. Soni. Nanoscale drug carriers bypass the blood-brain barrier. Mater. Today, 2015. IF 26.42, ISSN 13697021
2015
37.
B. Singh, A. Jain and S. Beg. Lipid-based nanostructured drug delivery systems for oral intake. Chronicle PharmaBiz-Special Issue: Nanomedicine. 2014, 14(6), 34-39. IF- NA, ISSN No – NA
2014
38.
B. Singh, S. Beg, G. Sharma, A. Jain and P. Negi. Holistic application of QbD for pharma product development excellence and regulatory compliance, Nirma Univ J Pharm Sci. 2014, 1(1), 19-35. IF , ISSN 2348 – 4012
2014
39.
S. Neekhra, S. Jain, S.A. Jain, N.K. Garg, A. Jain, V. Jain, P. Jain, and A. Jain. Anti- nociceptive activity of spirulina platensis in mice. Int J Pharmacogn. 2014, 1, 8, 507-510. IF NA, ISSN No – 2348-3962
2014
40.
S. Neekhra, V. Jain, P. Jain, S. Jain, S. A. Jain, A. Jain, and A. Jain. Assessment of anxiolytic potential of spirulina platensis. Int J Pharm Sci Res. 2015,70, 4061-4065. IF NA, ISSN No – 2394-1502.
2015
41.
R. Kaur, T. Sharma, R. Kaur, A. Jain and B. Singh. Delivering antimicrobial drugs to lungs through inhalation: An overview. Nov 2019 IF NA , ISSN
2019
42.
T. Sharma, R. Kaur, S. Saini, A. Jain and B. Singh. Strategic lipid-based delivery intervention for enhancing oral bioavailability of BCS II/IV drugs. Pharma Times, Sept 2019,51 IF NA , ISSN No 316849
2019

Awards & Achievements

GATE Qualified 2008 – AIR 199
2008
GATE Qualified 2007 – AIR 985
2007
UGC Junior Research Fellowship (JRF) for M.Pharm
Jaswant Singh Gill Fellowship, UIPS, Panjab University – Financial support during PhD
Sipra Innovation Travel Award, M/s Sipra Labs, Hyderabad
2016
HariRam Arora Award, Panjab University, Chandigarh – Best Scientific Publication
2018
Best Poster Presentation Award, IMTECH Chandigarh
2018
Dr. P.D. Sethi Award – Best Paper Publication in Pharmaceutical Analysis
2018
Best Oral Poster Presentation Award, IGNTU
2021

Paper / Poster Presentations