Educational Qualifications
M.Pharm , PhD(Pharmacy)
Area of Specialization / Research
Drug Repurposing using In silico, In vitro and In vivo techniques Meta-analysis Network Pharmacology Signal analysis in Pharmacovigilance
Notable Publications
- 1.
Sharma A and Kumar A* (2022). Identification of novel signal of clobazam‐associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis. Acta Neurologica Scandinavica. 146(5):623-627. Impact factor: 3.9. (Corresponding author).
2022 - 2.
Bhimaneni SP, and Kumar A* (2022). Abscisic acid and aloe-emodin against NS2B-NS3A protease of Japanese encephalitis virus. Environmental Science and Pollution Research 29 (6), 8759-8766. Impact factor: 5.1. (Corresponding author).
2022 - 3.
Sharma R, Patil CR, Kumar A*, Sharma, K. (2022). Identification of vaccine candidate against Omicron variant of SARS-CoV-2 using immunoinformatic approaches. In Silico Pharmacology 10(1), 1-16. (Corresponding author).
2022 - 4.
Jhanji R, Singh A, Kumar A* (2022). Antibacterial potential of selected phytomolecules: an experimental study. Microbiology and Immunology 65 (8), 325-332. Impact factor: 3.2. (Corresponding author).
2022 - 5.
Sharma N, Singh A, Sharma R, Kumar A* (2022). Repurposing of auranofin against bacterial infections: an in silico and in vitro study. Current Computer-Aided Drug Design 17 (5), 687-701. Impact factor: 1.6. (Corresponding author).
2022 - 6.
Garg A, Singh A, Kumar A* . (2022). Selective estrogen receptor modulators against gram-positive and gram-negative bacteria: an experimental study. Future microbiology 16 (13), 987-1001. Impact factor: 3.1. (Corresponding author).
2022 - 7.
Navyashree V and Kumar A* (2022). Acute toxicity study of 5, 11 dihydroindolo [3, 2-ß] carbazole as per OECD regulatory guidelines. Curr Drug Discov Technol, 10.2174/1570163819666220429095155. (Corresponding author).
2022 - 8.
SP Bhimaneni, Bhati V, Bhosale S, Kumar A*. (2021). Investigates interaction between abscisic acid and bovine serum albumin using various spectroscopic and in-silico techniques. Journal of Molecular Structure 1224, 129018. Impact factor: 3.8. (Corresponding author).
2021 - 9.
Deore MS, Naqvi S, Kumar A, Flora SJS. (2021). Alpha-lipoic acid protects co-exposure to lead and zinc oxide nanoparticles induced neuro, immuno and male reproductive toxicity in rats. 12, 1210. Impact factor: 5.9.
2021 - 10.
Bhosale S, and Kumar A* (2021). Screening of phytoconstituents of andrographis paniculata against various targets of japanese encephalitis virus: an in-silico and in-vitro target-based approach. Current Research in Pharmacology and Drug Discovery 2, 100043. (Corresponding author).
2021 - 11.
Gupta A, Kumar A , Naqvi S, Flora SJS. (2021). Chronic exposure to multi-metals on testicular toxicity in rats. Toxicology Mechanisms and Methods 31 (1), 53-66. Impact factor: 2.1.
2021 - 12.
Navyashree V, Kant K, Kumar A*. (2021) Natural chemical entities from Arisaema genus might be a promising break-through against Japanese encephalitis virus infection: a molecular docking and molecular dynamic studies. 39, 1404-1416. Impact factor: 3.3. (Corresponding author).
2021 - 13.
K Kant, R Rawat, V Bhati, S Bhosale, D Sharma, S Banerjee, Kumar A* (2021) Computational identification of natural product leads that inhibit mast cell chymase: an exclusive plausible treatment for Japanese encephalitis. 39 (4), 1203-1212. Impact factor: 3.3. (Corresponding author).
2021 - 14.
Rana A, Singh S, Deshmukh R and Kumar A*. (2020) Pharmacological potential of tocopherol and doxycycline against traumatic brain injury- induced cognitive/ motor impairment in rats. Brain injury. 34 (8), 1039-1050. Impact factor: 2.2. (Corresponding author).
2020 - 15.
Sharma S and Kumar A*. (2020) Evaluation of the Drug Utilization Pattern of Pre and Post Operative Medicines used in Surgical Department: A prospective observational study. Current Drug Therapy. 15, 389-395. (Corresponding author).
2020 - 16.
Verma A and Kumar A*. (2020) Risks associated with vortioxetine in the established therapeutic indication. Current Neuropharmacology.19(5), 711-717. Impact factor: 7.7. (Corresponding author).
2020 - 17.
Kant K, Rawat R, Bhati V, Bhosale S, Sharma D, Banerjee S and Kumar A *. (2020) Computational Identification of Natural Product Leads that Inhibit Mast Cell Chymase: An Exclusive Plausible Treatment for Japanese Encephalitis. Journal of biomolecular Structure Dynamics. 39(4), 1203-1212. Impact factor: 3.32. (Corresponding author).
2020 - 18.
Jhanji R, Bhati V, Singh A and Kumar A*. (2019) Phytomolecules against bacterial biofilm and efflux pump: An In silico and In vitro study. Journal of biomolecular Structure Dynamics. 38(18), 5500-5512. Impact factor: 3.32. (Corresponding author).
2019 - 19.
Chandel P, Kumar A, Singla N, Singh G and Kaur R. (2019) Rationally Synthesized Coumarin Based Pyrazolines ameliorates carrageenan induced inflammation through COX-2/Pro-inflammatory cytokine inhibition. Med Chem Comm. 10:421-430. Impact factor: 2.34.
2019 - 20.
Rana R, Sharma R, Kumar A*. (2019) Repurposing of Fluvastatin against Candida albicans CYP450 lanosterol 14 α-demethylase, a target enzyme for antifungal therapy: An In silico and In vitro study. Curr Mol Med. 19:506-524. Impact factor: 2.84. (Corresponding author).
2019 - 21.
Gupta M, Sharma R and Kumar A*. (2019). Comparative potential of Simvastatin, Rosuvastatin and Fluvastatin against bacterial infection: an in silico and in vitro study. Oriental Pharmacy and Experimental Medicine. 19:259-275. (Corresponding author).
2019 - 22.
Kumar A*, Gupta M, Sharma R, Sharma N. (2019). Deltamethrin-induced Immunotoxicity and its protection by Quercetin: An experimental study. Endocr Metab Immune Disord Drug Targets. 20(1), 67-76. Impact factor: 2.24. (First and Corresponding author).
2019 - 23.
Kant K, Lal UR, Kumar A *. and Ghosh M. (2019) A merged molecular docking, ADME-T and dynamics approaches towards the genus of Arisaema as herpes simplex virus type 1 and type 2 inhibitors. Computational biology and chemistry. 78:217-226 . Impact factor: 3.7. (Corresponding author).
2019 - 24.
Rana D, Sharma R and Kumar A*. (2018) Comparative potential of hydrocortisone, deoxycorticosterone and dexamethasone in the prevention of cataract: an in silico and in vitro study. Oriental Pharmacy and Experimental Medicine. 18:403-422. Impact factor: 0.44. (Corresponding author).
2018 - 25.
Kumar A* , Sharma R, Rana D and Sharma N. (2018) Protective effect of alpha-tocopherol in deltamethrin induced immunotoxicity. Endocr Metab Immune Disord Drug Targets. 19: 171-184. Impact factor: 2.24. (First author and Corresponding author).
2018 - 26.
Gupta M, Kant K, Sharma R and Kumar A*. (2018) Evaluation of In Silico Anti-parkinson potential of β-asarone. Central nervous system agents in medicinal chemistry. 18:128-135. (Corresponding author).
2018 - 27.
Kumar A , Behera P.C, Rangra N and Kant K. (2018) Computational Immunotoxic Assessment of Pyrethroid Insecticides against adaptive immune cell receptors. Pharmacognosy Magzine. 14:124-128. Impact factor: 1.24.
2018 - 28.
Mishra N, Sharma S, Deshmukh R, Kumar A , Sharma R. (2018) Development and Characterization of Nasal Delivery of Selegiline Hydrochloride Loaded Nanolipid Carriers for the Management of Parkinson’s Disease. Cent Nerv Syst Agents Med Chem. 19:46-56.
2018 - 29.
Kapoor Y, Sharma R and Kumar A*. (2018) Repurposing of existing drugs for the bacterial infections: An In silico and In vitro study. Infect Disord Drug Targets. doi: 10.2174/1871526519666181126094244. (Corresponding author).
2018 - 30.
Kumar A, Sasmal D and Sharma N. (2017) Mechanism of Deltamethrin induced thymic and splenic toxicity in mice and its protection by Piperine and Curcumin:in vivo study . Drug and Chemical Toxicology. 41: 33-41. Impact factor: 3.3 .
2017 - 31.
Sony JK, Ganguly S, Kumar P, Poddar R, Kumar A. (2017) Homology model, molecular dynamics simulation and novel pyrazole analogs design of Candida albicans CYP450 lanosterol 14 α-demethylase, a target enzyme for antifungal therapy. Journal of Biomolecular Structure Dynamics. 35: 1446-1463. Impact factor: 3.32 .
2017 - 32.
Kumar A, Sasmal D and Sharma N. (2016) Immunomodulatory role of piperine in deltamethrin induced thymic apoptosis and altered immune functions. Environmental Toxicology and Pharmacology. 39: 504-514. Impact factor: 4.8.
2016 - 33.
Kumar A and Sharma N. (2016) Comparative efficacy of piperine and curcumin in deltamethrin induced splenic apoptosis and altered immune functions. Pesticide Biochemistry and Physiology. 119:16-27. Impact factor: 4.9.
2016 - 34.
Kumar A, Sasmal D and Sharma N. (2015) Mechanism of immunoprotective effects of curcumin in dlm-induced thymic apoptosis and altered immune functions: anin silico and in vitro study. Journal of Immuntoxicology and Immunopharmacology. 37:488-498. Impact factor: 2.08.
2015 - 35.
Kumar A, Dubey R.K, Kant K, Sasmal D, Ghosh M, Sharma N. (2015) Determination of deltamethrin concentration in mice plasma and primary immune organs by simple reverse phase hplc. Acta Chromatographia. 28: 193-206. Impact factor: 2.0 .
2015 - 36.
Divakar D, Sasmal D, Kumar A*, Kumar A and Sharma N. (2015) Prophylactic role of piperine and curcumin in allethrin altered hematological and biochemical parameters in Swiss albino mice. Pharmacologia. 6: 396-412. (Corresponding author).
2015 - 37.
Kumar A, Sasmal D, Bhaskar A, Mukhopadhyay K, Thakur A and Sharma N. (2014) Deltamethrin induced oxidative stress and mitochondrial caspase dependent signaling pathways in murine splenocytes. Environmental Toxicology. 31: 808-819. Impact factor: 3.7.
2014 - 38.
Sharma N and Kumar A . (2014) Mechanism of immunotoxicological effects of tributyltin chloride on murine thymocytes. Cell Biology and Toxicology. 30: 101–112. Impact factor: 6.6.
2014 - 39.
Kumar A, Sasmal D and Sharma N. (2013) Deltamethrin induced an apoptogenic signalling pathway in murine thymocytes: exploring the molecular mechanism. Journal of Applied Toxicology. 34: 1303-1310. Impact factor: 3.4 .
2013 - 40.
Modugula H and Kumar A*. (2020) Risk analysis of lurasidone in patients with schizophrenia and bipolar depression. CNS neurological disorders drug targets. 19(2), 109-114. Impact factor:3.2 (Corresponding author).
2020 - 41.
Keerthana S and Kumar A*. (2020) Potential risks and benefits of zinc oxide nanoparticles: a systematic review. Critical Reviews in Toxicology.50(1), 47-71. Impact factor:5.3 (Corresponding author).
2020 - 42.
Bhimaneni SP and Kumar A* . (2020) Abscisic acid, a plant hormone, could be a promising candidate as an anti-Japanese encephalitis virus (JEV) agent. Anti-Infective Agents.18(4), 326-331. (Corresponding author).
2020 - 43.
Sharma R, Kant K and Kumar A*. (2019) Overview of Periodic Safety Update Reports: Where have We Reached?. Applied Clinical Research, Clinical Trials and Regulatory Affairs. 7(1), 4-11. (Corresponding author).
2019 - 44.
Garg A, Singh B, Singh A, Sharma R and Kumar A*. (2019) Selective Estrogen Receptor Modulators (SERMs): Mechanistic insights against resistant infections. Current Molecular Medicine. 20(2), 102-115. Impact factor:2.8 (Corresponding author).
2019 - 45.
Gupta M, Sharma R and Kumar A*. (2019) Docking Techniques in Toxicology: An overview. Current Bioinformatics. 15(6), 600-610. Impact factor:1.2 (Corresponding author).
2019 - 46.
Singh M and Kumar A*. (2019). Safety of SGLT2 Inhibitors in Patients with Diabetes Mellitus. Current drug safety. 14:87-93. (Corresponding author).
2019 - 47.
Gupta M, Sharma R and Kumar A*. (2018) Docking Techniques in Pharmacology:how much promising? Computational biology and chemistry. 76:210-217. Impact factor:1.6. (Corresponding author).
2018 - 48.
Gupta M and Kumar A*. (2018). Comparison of Minimum Inhibitory Concentration (MIC) value of statin drugs: A Systematic Review. Antiinfective agents. 17, 4-19. (Corresponding author).
2018 - 49.
Rana A, Singh S, Sharma R and Kumar A*. (2018) Traumatic Brain Injury altered Normal Brain Signaling Pathways: Implications for Novel Therapeutics approaches. Current Neuropharmacology. 17: 614-629. Impact factor:7.7. (Corresponding author).
2018 - 50.
Rana D and Kumar A*. (2018) Is there a role for Sodium orthovanadate in the treatment of diabetes? Current diabetic review. 15:284-287. Impact factor:3.5. (Corresponding author).
2018 - 51.
Garg A and Kumar A*. (2018). Risk and Benefit Profile of Dulaglutide in established therapeutic Indication. Current drug safety. 13:165-170. (Corresponding author).
2018 - 52.
Kumar A* and Khan H. (2016) Signal Detection and their Assessment in Pharmacovigilance. Open Pharmaceutical Sciences Journal. 2: 66-73. (Corresponding author).
2016 - 53.
Kumar A. (2016) Ebola virus altered innate and adaptive immune response signalingpathways: Implications for novel therapeutic approaches. Infectious disorders Drug Targets. 16: 79-94. (Single author).
2016 - 54.
Kumar A , Bhaskar A, Chandra S, Sasmal D, Mukhopadhyay K, Sharma N. (2015) Mechanism of Deltamethrin induced Immunotoxicity: Current and Future Perspectives. Receptors Clinical Investigation 2: e578. DOI: 10.14800/rci.578.
2015 - 55.
Jadav S.S, Kumar A, Ahsan M.J, Jayaprakash V. (2015) Ebola Virus: Current and Future Perspectives. Infectious Disorders Drug Targets. 15: 20-31.
2015 - 56.
Kumar A, Sharma N and Sasmal D. (2015). Understanding of statistics in testingofpharmacological hypothesis. Pharmawave. 8: 64-72.
2015 - 57.
1 . Kumar A, Sharma N, Singh S, Sasmal D and Dev A (2014) Oral vaccine antigen induced immune response signalling pathways: Current and future perspectives. Journal of Vaccine and Vaccination. 5: 225. DOI:10.4172/2157 7560.1000225. Impact factor: 1.50
2014 - 58.
Kumar A, Sasmal D and Sharma N. (2014) An insight into Deltamethrin induced apoptotic calcium, p53 and oxidative stress signalling pathways. Toxicology and Environmental Health Sciences. 7: 25-34.
2014 - 59.
Kumar A . (2022). Mucormycosis in COVID‐19 recovered patients. Journal of medical virology, 94(4), 1272-1273. Impact factor: 20.69.
2022 - 60.
Kumar A (2018). Risk and Benefit Analysis of Medicines. International Journal of Medical Sciences. Impact factor: 1.134 . Guest Editorial.
2018 - 61.
Kumar A (2014). Adaptive Immune System: Friend or Foe? Journal of harmonized research publications. Guest Editorial.
2014 - 62.
Kumar A (2015). Letter to editor: Immuno-oncology: Is it a new hope for cancer patients? Cancer studies and molecular medicine. 2: 66-68.
2015 - 63.
Kumar A. (2016). Efavirenz, a well known antiviral drug, might be a new option in the treatment of cancer. International Journal of Pharmacy and Pharmaceutical Sciences. Article in press.
2016 - 64.
Thakur M, Datusalia AK, Kumar A* (2022) Use of steroids in COVID-19 patients: A meta-analysis. European Journal of Pharmacology 914, 174579. Impact factor: 5.1 . (Corresponding author).
2022 - 65.
Sharma R, Kumar A* , Majeed J, Thakur AK, Aggarwal G. (2022). Drugs acting on the renin–angiotensin–aldosterone system (RAAS) and deaths of COVID-19 patients: a systematic review and meta-analysis of observational studies. 74(1), 1-21. Impact factor: 0.9 . (Corresponding author).
2022 - 66.
Singh AK, Vidyadhari A, Singh H, Haider K, Kumar A*, Sharma, M. (2022). Role of colchicine in the management of COVID-19 patients: A meta-analysis of cohort and randomized controlled trials. Clinical Epidemiology and Global Health, 16, 101097. (Corresponding author).
2022 - 67.
Singh AK, Kumar A, Agrawal N, Bhurani D, Ahmed R, Sharma M. (2022). Prevalence of anemia among chronic myeloid leukemia patients treated with Imatinib: A evidence based meta-analysis. Current Reviews in Clinical and Experimental Pharmacology.
2022 - 68.
Anuradha U, Kumar A , Singh RK. (2021) The clinical correlation of proinflammatory and anti-inflammatory biomarkers with Alzheimer disease: A meta-analysis. Neurological Sciences 43 (1), 285-298. Impact factor: 3.3 .
2021 - 69.
Srivastava R and Kumar A* (2021). Use of aspirin in reduction of mortality of COVID‐19 patients: A meta‐analysis. International journal of clinical practice 75 (11), e14515. Impact factor: 2.5 . (Corresponding author).
2021 - 70.
Vitalakumar D, Sharma A, Kumar A* , Flora SJS (2021) Neurological Manifestations in COVID-19 Patients: A Meta-Analysis. ACS Chemical Neuroscience. Impact factor: 5.7 . (Corresponding author).
2021 - 71.
Kumar A (2021). COVID-19: Current Challenges and Future Perspectives. Bentham Publisher. ISBN: 978-981-14-9863-3 (Print).
2021 - 72.
Kumar A and Sharma R (2021). Global Pharmacovigilance: Case Reporting to Aggregate Reporting. CBS Publisher. ISBN: 9789390709663.
2021 - 73.
Garg A, Sharma R, Dey P, Kumar A*. (2022). Food auto-oxidation: An overview. Antioxidants Effects in Health, 43-68. (Corresponding author).
2022 - 74.
Garg A, Kumar A *, Pottoo FH, Chawla PA. (2022). Animal Models Used for Studying the Benefits of Probiotics in Metabolic Disorders. In Probiotic Research in Therapeutics (pp. 261-275). Springer, Singapore. (Corresponding author).
2022 - 75.
Bhati V, Navyashree V, Singh S, Chawla P and Kumar A* (2020) Mathematical models for ADME of prodrugs. Recent Advancement in Prodrugs. Publisher: Tylor and Francis. (Corresponding author).
2020 - 76.
Kumar A and Flora SJS. (2019) Genome information of BW agents and their application in biodefence. Handbook on Biological Warfare Preparedness. Publisher: Elsevier. (In Press).
2019 - 77.
Garg A, Sharma R, Dey P and Kumar A*. (2019) Analysis of triterpenes and triterpenoids. Recent Advances in Natural Products Analysis. Publisher: Elsevier. (In Press). (Corresponding author).
2019 - 78.
Kumar A and Pillai J (2018). “Implantable Drug Delivery Systems: An Overview”. Book chapter in Nanostructures for the Engineering of Cells, Tissues and Organs : From Design to Applications, Elsevier Press. 473-511.
2018 - 79.
Sharma R, Gupta M and Kumar A* (2017). “Immunooncology: An overview”. Innovative Immunology. Austin Publishing Group. Volume 2. Page no. 1-14. ISBN: 978-0-9971499-1-3. (Corresponding author).
2017 - 80.
Kumar A , Sharma R and Rawal RK (2017). Phase IV clinical trial: An overview. Recent Advances in Clinical Trial. Centuary Publications. Page no. 64-93. ISBN: 978-93-85451-18-8.
2017 - 81.
Sharma R, Rath G, Kumar A, Goyal A.K. (2017) Success of clinical trial using small interfering RNA (replacement therapy). Page no. 143-176. ISBN: 978-93-85451-18-8.
2017
Awards & Achievements
Included as a top 2% Scientist of the World for the year 2021 in a study conducted by Stanford University, USA.
2021
Received an “Excellent Reviewer” award from Web of Science, Clarivate.
Received “Notable Researcher Award-2022” from DPSRU, New Delhi.
2022
Recognized as “Associate Editor” of Health Sciences Review Journal of Elsevier.
Recognized as “Assistant Editor” of Acta Neurologica Scandinavica Journal of Wiley.
Invited Lectures & Speaker Roles
Invited speaker in DST STUTI Program, Siksha O Anusandhan University, Odisha
2022
Chairperson at IBRO Meeting and Workshop - ISF College of Pharmacy, Moga, Punjab
2022
Resource person in workshop on Meta-analysis in Biomedical Research, R.C. Patel Institute
2022
Invited talk on Awareness on Epilepsy at Rotaract Club of DPSRU
2021
Invited talk on Aggregate reporting in Pharmacovigilance at National Coordination Centre, Pharmacovigilance Programme of India
2021
Lecturer at AICTE sponsored STTP on Computer-Aided Drug Design and Drug Repurposing, Jadavpur University, Kolkata
2021
Expert talk on Pharmacoeconomic modelling at Pharmaceutical Workshop Series, Chitkara University
2021
Lecturer on Meta-analysis of Nanomedicines at AICTE sponsored QIP, Birla Institute of Technology
2021
Expert talk on Disproportionality analysis in Pharmacovigilance, ISF College of Pharmacy, Moga
2021
Invited speaker at 31st Annual Conference, Society of Clinical Research Associates (SOCRA)
Book Chapters
- 1.
Food auto-oxidation: An overview — Antioxidants Effects in Health
2022 - 2.
Animal Models Used for Studying the Benefits of Probiotics in Metabolic Disorders — Probiotic Research in Therapeutics
Springer, Singapore2022 - 3.
Mathematical models for ADME of prodrugs — Recent Advancement in Prodrugs
Taylor and Francis2020 - 4.
Genome information of BW agents and their application in biodefence — Handbook on Biological Warfare Preparedness
Elsevier2019 - 5.
Analysis of triterpenes and triterpenoids — Recent Advances in Natural Products Analysis
Elsevier2019 - 6.
Implantable Drug Delivery Systems: An Overview — Nanostructures for the Engineering of Cells, Tissues and Organs
Elsevier Press2018 - 7.
Immunooncology: An overview — Innovative Immunology
Austin Publishing Group2017 - 8.
Phase IV clinical trial: An overview — Recent Advances in Clinical Trial
2017 - 9.
Success of clinical trial using small interfering RNA (replacement therapy) — Recent Advances in Clinical Trial
2017
Paper / Poster Presentations
- 1.
The Professional Society for Health Economics and Outcomes Research(ISPOR) life time membership.
- 2.
Society for Alternative to Animal Experiment(SAAE) life time membership.
Membership of Important Committees & Professional Associations
Life Member, International Society for Pharmacoeconomics and Outcomes Research (ISPOR)
Life Member, Society for Alternative to Animal Experiment (SAAE)
